PDB 4dff

PDB Links
Overview

PDB Information

PDB	4DFF
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	The SAR development of dihydroimidazoisoquinoline derivatives as phosphodiesterase 10A inhibitors for the treatment of schizophrenia. Ho, G.D., Michael Seganish, W., Bercovici, A., Tulshian, D., Greenlee, W.J., Van Rijn, R., Hruza, A., Xiao, L., Rindgen, D., Mullins, D., Guzzi, M., Zhang, X., Bleickardt, C., Hodgson, R. Bioorg.Med.Chem.Lett.
Header	Hydrolase/Hydrolase Inhibitor
Released	2012-01-23
Resolution	2.110
CATH Insert Date	27 May, 2012

PDB Images (5)

Image of CATH 4dff

4dff

PDB 4dff

Image of CATH 4dffA

4dffA

PDB Chain 4dffA

Image of CATH 4dffB

4dffB

PDB Chain 4dffB

Image of CATH 4dffA00

4dffA00

CATH Domain 4dffA00

Image of CATH 4dffB00

4dffB00

CATH Domain 4dffB00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	28 May, 2012	Chopped
B	28 May, 2012	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4dffA00	08 Feb, 2013	1.10.1300.10	Assigned
4dffB00	08 Feb, 2013	1.10.1300.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A