PDB 4d89
PDB Information
PDB | 4D89 |
Method | X-RAY DIFFRACTION |
Host Organism | Escherichia coli |
Gene Source | Homo sapiens |
Primary Citation | Discovery of cyclic sulfone hydroxyethylamines as potent and selective beta-site APP-cleaving enzyme 1 (BACE1) inhibitors: structure based design and in vivo reduction of amyloid beta-peptides
J.Med.Chem.
|
Header | Hydrolase/Hydrolase Inhibitor |
Released | 2012-01-10 |
Resolution | 1.650 |
CATH Insert Date | 02 Dec, 2012 |
PDB Images (4)
PDB Prints
PDB Chains (1)
Chain ID | Date inserted into CATH | CATH Status |
---|---|---|
A | 31 Dec, 2012 | Chopped |
CATH Domains (2)
Domain ID | Date inserted into CATH | Superfamily | CATH Status |
---|---|---|---|
4d89A01 | 03 Jan, 2013 | 2.40.70.10 | Assigned |
4d89A02 | 03 Jan, 2013 | 2.40.70.10 | Assigned |
UniProtKB Entries (1)
Accession | Gene ID | Taxon | Description |
---|---|---|---|
P56817 | BACE1_HUMAN | Homo sapiens | Beta-secretase 1 |