PDB 4d88
PDB Information
| PDB | 4D88 |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation | Discovery of cyclic sulfone hydroxyethylamines as potent and selective beta-site APP-cleaving enzyme 1 (BACE1) inhibitors: structure based design and in vivo reduction of amyloid beta-peptides
J.Med.Chem.
|
| Header | Hydrolase/Hydrolase Inhibitor |
| Released | 2012-01-10 |
| Resolution | 1.700 |
| CATH Insert Date | 02 Dec, 2012 |
PDB Prints
PDB Chains (1)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 31 Dec, 2012 | Chopped |
CATH Domains (2)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 4d88A01 | 03 Jan, 2013 | 2.40.70.10 | Assigned |
| 4d88A02 | 03 Jan, 2013 | 2.40.70.10 | Assigned |
UniProtKB Entries (1)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P56817 | BACE1_HUMAN | Homo sapiens | Beta-secretase 1 |
