PDB Information

PDB4D2S
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHOMO SAPIENS
Primary Citation
Discovery and Optimization of a Novel Series of Dyrk1B Kinase Inhibitors to Explore a Mek Resistance Hypothesis.
Kettle, J.G., Ballard, P., Bardelle, C., Cockerill, M., Colclough, N., Critchlow, S.E., Debreczeni, J.E., Fairley, G., Fillery, S., Graham, M.A., Goodwin, L., Guichard, S., Hudson, K., Ward, R.A., Whittaker, D.
J.Med.Chem.
HeaderTransferase
Released2014-05-12
Resolution2.500
CATH Insert Date28 Jun, 2015

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4d2sA01 10 Jul, 2015 3.30.200.20 Assigned
4d2sA02 10 Jul, 2015 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P33981 TTK_HUMAN Homo sapiens Dual specificity protein kinase TTK
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