PDB Information

PDB4CXX
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
A strategy based on nucleotide specificity leads to a subfamily-selective and cell-active inhibitor ofN6-methyladenosine demethylase FTO.
Toh, J.D.W., Sun, L., Lau, L.Z.M., Tan, J., Low, J.J.A., Tang, C.W.Q., Cheong, E.J.Y., Tan, M.J.H., Chen, Y., Hong, W., Gao, Y.G., Woon, E.C.Y.
Chem Sci
HeaderOxidoreductase
Released2014-04-09
Resolution2.760
CATH Insert Date19 Oct, 2014

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 20 Oct, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4cxxA01 21 Oct, 2014 2.60.120.590 Assigned
4cxxA02 21 Oct, 2014 1.20.58.1470 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q9C0B1 FTO_HUMAN Homo sapiens Alpha-ketoglutarate-dependent dioxygenase FTO
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