PDB Information

PDB4CCU
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHOMO SAPIENS
Primary Citation
The Design of Potent and Selective Inhibitors to Overcome Clinical Alk Mutations Resistant to Crizotinib.
Huang, Q., Johnson, T.W., Bailey, S., Brooun, A., Bunker, K.D., Burke, B.J., Collins, M.R., Cook, A., Cui, J.J., Dack, K.N., Deal, J.G., Deng, Y., Dinh, D.M., Engstrom, L.D., He, M., Hoffman, J., Hoffman, R.L., Shen, H., Johnson, P., Kania, R.S., Lam, H., Lam, J.L., Le, P., Li, Q., Lingardo, L., Liu, W., West Lu, M., Mctigue, M.A., Palmer, C.L., Richardson, P.F., Sach, N.W., Smeal, T., Smith, G.L., Stewart, A.E., Timofeevski, S.L., Tsaparikos, K., Wang, H., Zhu, H., Zhu, J., Zou, H.Y., Edwards, M.
J.Med.Chem.
HeaderTransferase
Released2013-10-28
Resolution2.000
CATH Insert Date02 Feb, 2014

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 03 Feb, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4ccuA01 07 Mar, 2014 3.30.200.20 Assigned
4ccuA02 07 Mar, 2014 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q9UM73 ALK_HUMAN Homo sapiens ALK tyrosine kinase receptor
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