PDB 4c66

PDB Information

PDB4C66
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Discovery of Epigenetic Regulator I-Bet762: Lead Optimization to Afford a Clinical Candidate Inhibitor of the Bet Bromodomains.
Mirguet, O., Gosmini, R., Toum, J., Clement, C., Barnathan, M., Brusq, J., Mordaunt, J.E., Grimes, R., Crowe, M., Pineau, O., Ajakane, M., Daugan, A., Jeffrey, P., Cutler, L., Haynes, A., Smithers, N., Chung, C., Bamborough, P., Uings, I.J., Lewis, T., Witherington, J., Parr, N., Prinjha, R., Nicodeme, E.
J.Med.Chem.
HeaderCell Cycle
Released2013-09-17
Resolution1.870
CATH Insert Date06 Oct, 2013

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 07 Oct, 2013 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4c66A01 10 Oct, 2013 1.20.920.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O60885 BRD4_HUMAN Homo sapiens Bromodomain-containing protein 4
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