PDB Information

PDB4BYJ
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Aurora Isoform Selectivity: Design and Synthesis of Imidazo[4,5-B]Pyridine Derivatives as Highly Selective Inhibitors of Aurora-A Kinase in Cells.
Bavetsias, V., Faisal, A., Crumpler, S., Brown, N., Kosmopoulou, M., Joshi, A., Atrash, B., Perez-Fuertes, Y., Schmitt, J.A., Boxall, K.J., Burke, R., Sun, C., Avery, S., Bush, K., Henley, A., Raynaud, F.I., Workman, P., Bayliss, R., Linardopoulos, S., Blagg, J.
J.Med.Chem.
HeaderTransferase
Released2013-07-19
Resolution2.750
CATH Insert Date24 Nov, 2013

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 25 Nov, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4byjA01 27 Nov, 2013 3.30.200.20 Assigned
4byjA02 27 Nov, 2013 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O14965 AURKA_HUMAN Homo sapiens Aurora kinase A