PDB 4bti

PDB Links
Overview

PDB Information

PDB	4BTI
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	5-Chlorothiophene-2-Carboxylic Acid [(S)-2-[2-Methyl-3-(2-Oxopyrrolidin-1-Yl)Benzenesulfonylamino]-3-(4-Methylpiperazin-1-Yl)-3-Oxopropyl]Amide (Sar107375), a Selective and Potent Orally Active Dual Thrombin and Factor Xa Inhibitor. Meneyrol, J., Follmann, M., Lassalle, G., Wehner, V., Barre, G., Rousseaux, T., Altenburger, J., Petit, F., Bocskei, Z., Schreuder, H., Alet, N., Herault, J., Millet, L., Dol, F., Florian, P., Schaeffer, P., Sadoun, F., Klieber, S., Briot, C., Bono, F., Herbert, J. J.Med.Chem.
Header	Hydrolase
Released	2013-06-18
Resolution	2.300
CATH Insert Date	05 Jan, 2014

PDB Images (11)

Image of CATH 4bti

4bti

PDB 4bti

Image of CATH 4btiA

4btiA

PDB Chain 4btiA

Image of CATH 4btiB

4btiB

PDB Chain 4btiB

Image of CATH 4btiE

4btiE

PDB Chain 4btiE

Image of CATH 4btiF

4btiF

PDB Chain 4btiF

Image of CATH 4btiA00

4btiA00

CATH Domain 4btiA00

Image of CATH 4btiB01

4btiB01

CATH Domain 4btiB01

Image of CATH 4btiB02

4btiB02

CATH Domain 4btiB02

Image of CATH 4btiE00

4btiE00

CATH Domain 4btiE00

Image of CATH 4btiF01

4btiF01

CATH Domain 4btiF01

Image of CATH 4btiF02

4btiF02

CATH Domain 4btiF02

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	06 Jan, 2014	Chopped
B	06 Jan, 2014	Chopped
E	06 Jan, 2014	Chopped
F	06 Jan, 2014	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4btiA00	09 Jan, 2014	2.10.25.10	Assigned
4btiB01	09 Jan, 2014	2.40.10.10	Assigned
4btiB02	09 Jan, 2014	2.40.10.10	Assigned
4btiE00	09 Jan, 2014	2.10.25.10	Assigned
4btiF01	09 Jan, 2014	2.40.10.10	Assigned
4btiF02	09 Jan, 2014	2.40.10.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
P00742	FA10_HUMAN	Homo sapiens	Coagulation factor X
P00742	FA10_HUMAN	Homo sapiens	Coagulation factor X
P00742	FA10_HUMAN	Homo sapiens	Coagulation factor X
P00742	FA10_HUMAN	Homo sapiens	Coagulation factor X