PDB 4bcm

PDB Information

PDB4BCM
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Comparative Structural and Functional Studies of 4-(Thiazol- 5-Yl)-2-(Phenylamino)Pyrimidine-5-Carbonitrile Cdk9 Inhibitors Suggest the Basis for Isotype Selectivity.
Hole, A.J., Baumli, S., Shao, H., Shi, S., Pepper, C., Fischer, P.M., Wang, S., Endicott, J.A., Noble, M.E.M.
J.Med.Chem.
HeaderTransferase/Cell Cycle
Released2012-10-02
Resolution2.450
CATH Insert Date28 Mar, 2013

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 28 Mar, 2013 Chopped
B 28 Mar, 2013 Chopped
C 28 Mar, 2013 Chopped
D 28 Mar, 2013 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4bcmA01 11 Apr, 2013 3.30.200.20 Assigned
4bcmA02 11 Apr, 2013 1.10.510.10 Assigned
4bcmB01 10 Apr, 2013 1.10.472.10 Assigned
4bcmB02 10 Apr, 2013 1.10.472.10 Assigned
4bcmC01 10 Apr, 2013 3.30.200.20 Assigned
4bcmC02 10 Apr, 2013 1.10.510.10 Assigned
4bcmD01 10 Apr, 2013 1.10.472.10 Assigned
4bcmD02 10 Apr, 2013 1.10.472.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2