PDB 4bck

PDB Information

PDB4BCK
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Comparative Structural and Functional Studies of 4-(Thiazol- 5-Yl)-2-(Phenylamino)Pyrimidine-5-Carbonitrile Cdk9 Inhibitors Suggest the Basis for Isotype Selectivity.
Hole, A.J., Baumli, S., Shao, H., Shi, S., Pepper, C., Fischer, P.M., Wang, S., Endicott, J.A., Noble, M.E.M.
J.Med.Chem.
HeaderTransferase/Cell Cycle
Released2012-10-02
Resolution2.050
CATH Insert Date28 Mar, 2013

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 28 Mar, 2013 Chopped
B 28 Mar, 2013 Chopped
C 28 Mar, 2013 Chopped
D 28 Mar, 2013 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4bckA01 10 Apr, 2013 3.30.200.20 Assigned
4bckA02 10 Apr, 2013 1.10.510.10 Assigned
4bckB01 10 Apr, 2013 1.10.472.10 Assigned
4bckB02 10 Apr, 2013 1.10.472.10 Assigned
4bckC01 11 Apr, 2013 3.30.200.20 Assigned
4bckC02 11 Apr, 2013 1.10.510.10 Assigned
4bckD01 10 Apr, 2013 1.10.472.10 Assigned
4bckD02 10 Apr, 2013 1.10.472.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2