PDB Information

PDB4BCG
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHOMO SAPIENS
Primary Citation
Substituted 4-(Thiazol-5-Yl)-2-(Phenylamino)Pyrimidines are Highly Active Cdk9 Inhibitors: Synthesis, X-Ray Crystal Structure, Sar and Anti-Cancer Activities.
Shao, H., Shi, S., Huang, S., Hole, A., Abbas, A.Y., Baumli, S., Liu, X., Lam, F., Foley, D.W., Fischer, P.M., Noble, M., Endicott, J.A., Pepper, C., Wang, S.
J.Med.Chem.
HeaderTransferase/Cell Cycle
Released2012-10-02
Resolution3.090
CATH Insert Date07 Jul, 2013

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 Jul, 2013 Chopped
B 08 Jul, 2013 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4bcgA01 09 Aug, 2013 3.30.200.20 Assigned
4bcgA02 09 Aug, 2013 1.10.510.10 Assigned
4bcgB01 09 Aug, 2013 1.10.472.10 Assigned
4bcgB02 09 Aug, 2013 1.10.472.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P50750 CDK9_HUMAN Homo sapiens Cyclin-dependent kinase 9
O60563 CCNT1_HUMAN Homo sapiens Cyclin-T1
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