PDB 4b05

PDB Information

PDB4B05
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Discovery of AZD3839, a potent and selective BACE1 inhibitor clinical candidate for the treatment of Alzheimer disease.
Jeppsson, F., Eketjall, S., Janson, J., Karlstrom, S., Gustavsson, S., Olsson, L.L., Radesater, A.C., Ploeger, B., Cebers, G., Kolmodin, K., Swahn, B.M., von Berg, S., Bueters, T., Falting, J.
J. Biol. Chem.
HeaderHydrolase
Released2012-06-28
Resolution1.800
CATH Insert Date04 Nov, 2012

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4b05A01 10 Nov, 2012 2.40.70.10 Assigned
4b05A02 10 Nov, 2012 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
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