PDB 4axa

PDB Information

PDB4AXA
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceBOS TAURUS
Primary Citation
At13148 is a Novel, Oral Multi-Agc Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity.
Yap, T.A., Walton, M.I., Grimshaw, K.M., Te Poele, R.H., Eve, P.D., Valenti, M.R., De Haven Brandon, A.K., Martins, V., Zetterlund, A., Heaton, S.P., Heinzmann, K., Jones, P.S., Feltell, R.E., Reule, M., Woodhead, S.J., Davies, T.G., Lyons, J.F., Raynaud, F.I., Eccles, S.A., Workman, P., Thompson, N.T., Garrett, M.D.
Clin.Cancer Res.
HeaderTransferase/Transferase Inhibitor
Released2012-06-12
Resolution1.900
CATH Insert Date04 Nov, 2012

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped
I 05 Nov, 2012 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4axaA01 30 Aug, 2013 1.10.510.10 Assigned
4axaA02 30 Aug, 2013 3.30.200.20 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P00517 KAPCA_BOVIN Bos taurus cAMP-dependent protein kinase catalytic subunit alpha