PDB Information

PDB4ANL
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHOMO SAPIENS
Primary Citation
Design of Potent and Selective Inhibitors to Overcome Clinical Anaplastic Lymphoma Kinase Mutations Resistant to Crizotinib.
Huang, Q., Johnson, T.W., Bailey, S., Brooun, A., Bunker, K.D., Burke, B.J., Collins, M.R., Cook, A.S., Cui, J.J., Dack, K.N., Deal, J.G., Deng, Y., Dinh, D., Engstrom, L.D., He, M., Hoffman, J., Hoffman, R.L., Johnson, P.S., Kania, R.S., Lam, H., Lam, J.L., Le, P.T., Li, Q., Lingardo, L., Liu, W., Lu, M.W., Mctigue, M., Palmer, C.L., Richardson, P.F., Sach, N.W., Shen, H., Smeal, T., Smith, G.L., Stewart, A.E., Timofeevski, S., Tsaparikos, K., Wang, H., Zhu, H., Zhu, J., Zou, H.Y., Edwards, M.P.
J.Med.Chem.
HeaderTransferase
Released2012-03-20
Resolution1.700
CATH Insert Date07 Jul, 2013

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 08 Jul, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4anlA01 08 Aug, 2013 3.30.200.20 Assigned
4anlA02 08 Aug, 2013 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q9UM73 ALK_HUMAN Homo sapiens ALK tyrosine kinase receptor
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