PDB 4an3

PDB Information

PDB4AN3
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHOMO SAPIENS
Primary Citation
Novel Carboxamide-Based Allosteric Mek Inhibitors: Discovery and Optimization Efforts Toward Xl518 (Gdc-0973)
Rice, K.D., Aay, N., Anand, N.K., Blazey, C.M., Bowles, O.J., Bussenius, J., Costanzo, S., Curtis, J.K., Defina, S.C., Dubenko, L., Engst, S., Joshi, A.A., Kennedy, A.R., Kim, A.I., Koltun, E.S., Lougheed, J.C., Manalo, J.C.L., Martini, J.F., Nuss, J.M., Peto, C.J., Tsang, T.H., Yu, P., Johnston, S.
Acs Med.Chem.Lett.
HeaderTransferase
Released2012-03-15
Resolution2.100
CATH Insert Date30 Dec, 2012

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 31 Dec, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4an3A01 08 Oct, 2013 3.30.200.20 Assigned
4an3A02 08 Oct, 2013 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q02750 MP2K1_HUMAN Homo sapiens Dual specificity mitogen-activated protein kinase kinase 1