PDB 4aj1

PDB Information

PDB4AJ1
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceRATTUS NORVEGICUS
Primary Citation
The Design and Synthesis of Novel Lactate Dehydrogenase a Inhibitors by Fragment-Based Lead Generation
Ward, R., Brassington, C., Breeze, A.L., Caputo, A., Critchlow, S., Davies, G., Goodwin, L., Hassall, G., Greenwood, R., Holdgate, G., Mrosek, M., Norman, R.A., Pearson, S., Tart, J., Tucker, J.A., Vogtherr, M., Whittaker, D., Wingfield, J., Winter, J., Hudson, K.
J.Med.Chem.
HeaderOxidoreductase/Inhibitor
Released2012-02-15
Resolution1.870
CATH Insert Date27 May, 2012

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 28 May, 2012 Chopped
B 28 May, 2012 Chopped
C 28 May, 2012 Chopped
D 28 May, 2012 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4aj1A01 01 Feb, 2013 3.40.50.720 Assigned
4aj1A02 01 Feb, 2013 3.90.110.10 Assigned
4aj1B01 01 Feb, 2013 3.40.50.720 Assigned
4aj1B02 01 Feb, 2013 3.90.110.10 Assigned
4aj1C01 01 Feb, 2013 3.40.50.720 Assigned
4aj1C02 01 Feb, 2013 3.90.110.10 Assigned
4aj1D01 01 Feb, 2013 3.40.50.720 Assigned
4aj1D02 01 Feb, 2013 3.90.110.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P04642 LDHA_RAT Rattus norvegicus L-lactate dehydrogenase A chain
P04642 LDHA_RAT Rattus norvegicus L-lactate dehydrogenase A chain
P04642 LDHA_RAT Rattus norvegicus L-lactate dehydrogenase A chain
P04642 LDHA_RAT Rattus norvegicus L-lactate dehydrogenase A chain
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