PDB Information

PDB4AI9
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases.
Rose, N.R., Woon, E.C., Tumber, A., Walport, L.J., Chowdhury, R., Li, X.S., King, O.N., Lejeune, C., Ng, S.S., Krojer, T., Chan, M.C., Rydzik, A.M., Hopkinson, R.J., Che, K.H., Daniel, M., Strain-Damerell, C., Gileadi, C., Kochan, G., Leung, I.K., Dunford, J., Yeoh, K.K., Ratcliffe, P.J., Burgess-Brown, N., von Delft, F., Muller, S., Marsden, B., Brennan, P.E., McDonough, M.A., Oppermann, U., Klose, R.J., Schofield, C.J., Kawamura, A.
J. Med. Chem.
HeaderOxidoreductase
Released2012-02-08
Resolution2.250
CATH Insert Date04 Nov, 2012

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped
B 05 Nov, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4ai9A01 30 Aug, 2013 2.60.120.650 Assigned
4ai9B01 30 Aug, 2013 2.60.120.650 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O75164 KDM4A_HUMAN Homo sapiens Lysine-specific demethylase 4A
O75164 KDM4A_HUMAN Homo sapiens Lysine-specific demethylase 4A