Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases.
Rose, N.R., Woon, E.C., Tumber, A., Walport, L.J., Chowdhury, R., Li, X.S., King, O.N., Lejeune, C., Ng, S.S., Krojer, T., Chan, M.C., Rydzik, A.M., Hopkinson, R.J., Che, K.H., Daniel, M., Strain-Damerell, C., Gileadi, C., Kochan, G., Leung, I.K., Dunford, J., Yeoh, K.K., Ratcliffe, P.J., Burgess-Brown, N., von Delft, F., Muller, S., Marsden, B., Brennan, P.E., McDonough, M.A., Oppermann, U., Klose, R.J., Schofield, C.J., Kawamura, A.
J. Med. Chem.