PDB 4ai8

PDB Information

PDB4AI8
MethodX-RAY DIFFRACTION
Host Organism Escherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases.
Rose, N.R., Woon, E.C., Tumber, A., Walport, L.J., Chowdhury, R., Li, X.S., King, O.N., Lejeune, C., Ng, S.S., Krojer, T., Chan, M.C., Rydzik, A.M., Hopkinson, R.J., Che, K.H., Daniel, M., Strain-Damerell, C., Gileadi, C., Kochan, G., Leung, I.K., Dunford, J., Yeoh, K.K., Ratcliffe, P.J., Burgess-Brown, N., von Delft, F., Muller, S., Marsden, B., Brennan, P.E., McDonough, M.A., Oppermann, U., Klose, R.J., Schofield, C.J., Kawamura, A.
J. Med. Chem.
HeaderOxidoreductase
Released2012-02-08
Resolution2.400
CATH Insert Date04 Nov, 2012

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4ai8A01 10 Nov, 2012 2.60.120.10 Assigned
4ai8A02 10 Nov, 2012 1.10.287.1010 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q9NWT6 HIF1N_HUMAN Homo sapiens Hypoxia-inducible factor 1-alpha inhibitor