PDB 4afe

PDB Information

PDB4AFE
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Design of Potent and Selective Hybrid Inhibitors of the Mitotic Kinase Nek2: Structure-Activity Relationship, Structural Biology, and Cellular Activity.
Innocenti, P., Cheung, K.M., Solanki, S., Mas-Droux, C., Rowan, F., Yeoh, S., Boxall, K., Westlake, M., Pickard, L., Hardy, T., Baxter, J.E., Aherne, G.W., Bayliss, R., Fry, A.M., Hoelder, S.
J.Med.Chem.
HeaderTransferase
Released2012-01-19
Resolution2.600
CATH Insert Date27 May, 2012

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 28 May, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4afeA01 08 Jun, 2012 3.30.200.20 Assigned
4afeA02 08 Jun, 2012 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P51955 NEK2_HUMAN Homo sapiens Serine/threonine-protein kinase Nek2