PDB Information

PDB4ACU
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Aminoimidazoles as BACE-1 inhibitors: the challenge to achieve in vivo brain efficacy.
Swahn, B.M., Holenz, J., Kihlstrom, J., Kolmodin, K., Lindstrom, J., Plobeck, N., Rotticci, D., Sehgelmeble, F., Sundstrom, M., Berg, S.v., Falting, J., Georgievska, B., Gustavsson, S., Neelissen, J., Ek, M., Olsson, L.L., Berg, S.
Bioorg. Med. Chem. Lett.
HeaderHydrolase
Released2011-12-19
Resolution1.750
CATH Insert Date27 May, 2012

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 28 May, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4acuA01 08 Jun, 2012 2.40.70.10 Assigned
4acuA02 08 Jun, 2012 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1