PDB Information

PDB4A5S
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHOMO SAPIENS
Primary Citation
Novel Heterocyclic Dpp-4 Inhibitors for the Treatment of Type 2 Diabetes.
Sutton, J.M., Clark, D.E., Dunsdon, S.J., Fenton, G., Fillmore, A., Harris, N.V., Higgs, C., Hurley, C.A., Krintel, S.L., Mackenzie, R.E., Duttaroy, A., Gangl, E., Maniara, W., Sedrani, R., Namoto, K., Ostermann, N., Gerhartz, B., Sirockin, F., Trappe, J., Hassiepen, U., Baeschlin, D.K.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2011-10-28
Resolution1.620
CATH Insert Date12 Feb, 2012

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 13 Feb, 2012 Chopped
B 13 Feb, 2012 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4a5sA01 15 Feb, 2012 3.40.50.1820 Assigned
4a5sA02 15 Feb, 2012 2.140.10.30 Assigned
4a5sB01 16 Feb, 2012 3.40.50.1820 Assigned
4a5sB02 16 Feb, 2012 2.140.10.30 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P27487 DPP4_HUMAN Homo sapiens Dipeptidyl peptidase 4
P27487 DPP4_HUMAN Homo sapiens Dipeptidyl peptidase 4
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