PDB Information

PDB3ZIM
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHOMO SAPIENS
Primary Citation
Discovery of a Potent and Isoform-Selective Targeted Covalent Inhibitor of the Lipid Kinase Pi3Kalpha
Nacht, M., Qiao, L., Sheets, M.P., Martin, T.S., Labenski, M., Mazdiyasni, H., Karp, R., Zhu, Z., Chaturvedi, P., Bhavsar, D., Niu, D., Westlin, W., Petter, R.C., Medikonda, A.P., Singh, J.
J.Med.Chem.
HeaderTransferase
Released2013-01-09
Resolution2.850
CATH Insert Date28 Mar, 2013

PDB Images (7)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 28 Mar, 2013 Chopped

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
3zimA01 21 Nov, 2013 3.10.20.90 Assigned
3zimA02 21 Nov, 2013 2.60.40.150 Assigned
3zimA03 21 Nov, 2013 1.25.40.70 Assigned
3zimA04 21 Nov, 2013 3.30.1010.10 Assigned
3zimA05 21 Nov, 2013 1.10.1070.11 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P42336 PK3CA_HUMAN Homo sapiens Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
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