PDB Information

PDB3ZBX
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHOMO SAPIENS
Primary Citation
Lessons from (S)-6-(1-(6-(1-Methyl-1H-Pyrazol-4-Yl)-[1,2, 4]Triazolo[4,3-B]Pyridazin-3-Yl)Ethyl)Quinoline (Pf-04254644), an Inhibitor of Receptor Tyrosine Kinase C-met with High Protein Kinase Selectivity But Broad Phosphodiesterase Family Inhibition Leading to Myocardial Degeneration in Rats.
Cui, J.J., Shen, H., Tran-Dube, M., Nambu, M., Mctigue, M., Grodsky, N., Ryan, K., Yamazaki, S., Aguirre, S., Parker, M., Li, Q., Zou, H., Christensen, J.
J.Med.Chem.
HeaderTransferase
Released2012-11-13
Resolution2.200
CATH Insert Date01 Dec, 2013

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 02 Dec, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3zbxA01 04 Dec, 2013 3.30.200.20 Assigned
3zbxA02 04 Dec, 2013 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P08581 MET_HUMAN Homo sapiens Hepatocyte growth factor receptor