PDB 3vv7

PDB Information

PDB3VV7
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Conformational restriction approach to beta-secretase (BACE1) inhibitors: effect of a cyclopropane ring to induce an alternative binding mode.
Yonezawa, S., Yamamoto, T., Yamakawa, H., Muto, C., Hosono, M., Hattori, K., Higashino, K., Yutsudo, T., Iwamoto, H., Kondo, Y., Sakagami, M., Togame, H., Tanaka, Y., Nakano, T., Takemoto, H., Arisawa, M., Shuto, S.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2012-07-17
Resolution2.100
CATH Insert Date04 Nov, 2012

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3vv7A01 11 Nov, 2012 2.40.70.10 Assigned
3vv7A02 11 Nov, 2012 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1