PDB Information

PDB3VJK
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery and preclinical profile of teneligliptin (3-[(2S,4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl]pyrrolidin-2-ylcarbonyl]thiazolidine): A highly potent, selective, long-lasting and orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes
Yoshida, T., Akahoshi, F., Sakashita, H., Kitajima, H., Nakamura, M., Sonda, S., Takeuchi, M., Tanaka, Y., Ueda, N., Sekiguchi, S., Ishige, T., Shima, K., Nabeno, M., Abe, Y., Anabuki, J., Soejima, A., Yoshida, K., Takashina, Y., Ishii, S., Kiuchi, S., Fukuda, S., Tsutsumiuchi, R., Kosaka, K., Murozono, T., Nakamaru, Y., Utsumi, H., Masutomi, N., Kishida, H., Miyaguchi, I., Hayashi, Y.
Bioorg.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2011-10-24
Resolution2.490
CATH Insert Date04 Nov, 2012

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped
B 05 Nov, 2012 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3vjkA01 10 Nov, 2012 2.140.10.30 Assigned
3vjkA02 10 Nov, 2012 3.40.50.1820 Assigned
3vjkB01 10 Nov, 2012 2.140.10.30 Assigned
3vjkB02 10 Nov, 2012 3.40.50.1820 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P27487 DPP4_HUMAN Homo sapiens Dipeptidyl peptidase 4
P27487 DPP4_HUMAN Homo sapiens Dipeptidyl peptidase 4
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