PDB Information

PDB3V5Q
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of GNF-5837, a Selective TRK Inhibitor with Efficacy in Rodent Cancer Tumor Models.
Albaugh, P., Fan, Y., Mi, Y., Sun, F., Adrian, F., Li, N., Jia, Y., Sarkisova, Y., Kreusch, A., Hood, T., Lu, M., Liu, G., Huang, S., Liu, Z., Loren, J., Tuntland, T., Karanewsky, D.S., Seidel, H.M., Molteni, V.
ACS Med Chem Lett
HeaderTransferase/Transferase Inhibitor
Released2011-12-16
Resolution2.200
CATH Insert Date12 Feb, 2012

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 13 Feb, 2012 Chopped
B 13 Feb, 2012 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3v5qA01 16 Feb, 2012 3.30.200.20 Assigned
3v5qA02 16 Feb, 2012 1.10.510.10 Assigned
3v5qB01 15 Feb, 2012 3.30.200.20 Assigned
3v5qB02 15 Feb, 2012 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q16288 NTRK3_HUMAN Homo sapiens NT-3 growth factor receptor
Q16288 NTRK3_HUMAN Homo sapiens NT-3 growth factor receptor