PDB Information

PDB3U1Y
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourcePseudomonas aeruginosa
Primary Citation
Potent inhibitors of LpxC for the treatment of Gram-negative infections.
Brown, M.F., Reilly, U., Abramite, J.A., Arcari, J.T., Oliver, R., Barham, R.A., Che, Y., Chen, J.M., Collantes, E.M., Chung, S.W., Desbonnet, C., Doty, J., Doroski, M., Engtrakul, J.J., Harris, T.M., Huband, M., Knafels, J.D., Leach, K.L., Liu, S., Marfat, A., Marra, A., McElroy, E., Melnick, M., Menard, C.A., Montgomery, J.I., Mullins, L., Noe, M.C., O'Donnell, J., Penzien, J., Plummer, M.S., Price, L.M., Shanmugasundaram, V., Thoma, C., Uccello, D.P., Warmus, J.S., Wishka, D.G.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2011-09-30
Resolution2.000
CATH Insert Date08 Jan, 2012

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 09 Jan, 2012 Chopped
B 09 Jan, 2012 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3u1yA01 04 Feb, 2013 3.30.230.20 Assigned
3u1yA02 04 Feb, 2013 3.30.1700.10 Assigned
3u1yB01 04 Feb, 2013 3.30.230.20 Assigned
3u1yB02 04 Feb, 2013 3.30.1700.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P47205 LPXC_PSEAE Pseudomonas aeruginosa PAO1 UDP-3-O-acyl-N-acetylglucosamine deacetylase
P47205 LPXC_PSEAE Pseudomonas aeruginosa PAO1 UDP-3-O-acyl-N-acetylglucosamine deacetylase