PDB Information

PDB3T8M
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Rational Design of PI3K-alpha Inhibitors that Exhibit Selectivity Over the PI3K-beta Isoform
Heffron, T., Wei, B., Olivero, A.G., Staben, S.T., Tsui, V., Do, S., Dotson, J., Folkes, A., Goldsmith, A., Goldsmith, R., Gunzner, J., Lesnick, J., Lewis, C., Mathieu, S., Nonomiya, J., Sutherlin, D.P., Wan, N.C., Wang, S., Weismann, C., Zhu, B.
To be Published
HeaderTransferase/Transferase Inhibitor
Released2011-08-01
Resolution2.500
CATH Insert Date20 Nov, 2011

PDB Images (7)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 29 Nov, 2011 Chopped

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
3t8mA01 04 Sep, 2013 3.10.20.90 Assigned
3t8mA02 04 Sep, 2013 2.60.40.150 Assigned
3t8mA03 04 Sep, 2013 1.25.40.70 Assigned
3t8mA04 04 Sep, 2013 3.30.1010.10 Assigned
3t8mA05 04 Sep, 2013 1.10.1070.11 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P48736 PK3CG_HUMAN Homo sapiens Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
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