PDB 3sl5

PDB Links
Overview

PDB Information

PDB	3SL5
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Thiophene inhibitors of PDE4: Crystal structures show a second binding mode at the catalytic domain of PDE4D2. Nankervis, J.L., Feil, S.C., Hancock, N.C., Zheng, Z., Ng, H.L., Morton, C.J., Holien, J.K., Ho, P.W., Frazzetto, M.M., Jennings, I.G., Manallack, D.T., Martin, T.J., Thompson, P.E., Parker, M.W. Bioorg.Med.Chem.Lett.
Header	Hydrolase/Hydrolase Inhibitor
Released	2011-06-24
Resolution	2.650
CATH Insert Date	30 Oct, 2011

PDB Images (9)

Image of CATH 3sl5

3sl5

PDB 3sl5

Image of CATH 3sl5A

3sl5A

PDB Chain 3sl5A

Image of CATH 3sl5B

3sl5B

PDB Chain 3sl5B

Image of CATH 3sl5C

3sl5C

PDB Chain 3sl5C

Image of CATH 3sl5D

3sl5D

PDB Chain 3sl5D

Image of CATH 3sl5A00

3sl5A00

CATH Domain 3sl5A00

Image of CATH 3sl5B00

3sl5B00

CATH Domain 3sl5B00

Image of CATH 3sl5C00

3sl5C00

CATH Domain 3sl5C00

Image of CATH 3sl5D00

3sl5D00

CATH Domain 3sl5D00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	29 Nov, 2011	Chopped
B	29 Nov, 2011	Chopped
C	29 Nov, 2011	Chopped
D	29 Nov, 2011	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3sl5A00	25 Apr, 2013	1.10.1300.10	Assigned
3sl5B00	25 Apr, 2013	1.10.1300.10	Assigned
3sl5C00	25 Apr, 2013	1.10.1300.10	Assigned
3sl5D00	25 Apr, 2013	1.10.1300.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
Q08499	PDE4D_HUMAN	Homo sapiens	cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Q08499	PDE4D_HUMAN	Homo sapiens	cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Q08499	PDE4D_HUMAN	Homo sapiens	cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Q08499	PDE4D_HUMAN	Homo sapiens	cAMP-specific 3',5'-cyclic phosphodiesterase 4D