PDB 3sl3

PDB Links
Overview

PDB Information

PDB	3SL3
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Thiophene inhibitors of PDE4: Crystal structures show a second binding mode at the catalytic domain of PDE4D2. Nankervis, J.L., Feil, S.C., Hancock, N.C., Zheng, Z., Ng, H.L., Morton, C.J., Holien, J.K., Ho, P.W., Frazzetto, M.M., Jennings, I.G., Manallack, D.T., Martin, T.J., Thompson, P.E., Parker, M.W. Bioorg.Med.Chem.Lett.
Header	Hydrolase
Released	2011-06-24
Resolution	2.100
CATH Insert Date	30 Oct, 2011

PDB Images (9)

Image of CATH 3sl3

3sl3

PDB 3sl3

Image of CATH 3sl3A

3sl3A

PDB Chain 3sl3A

Image of CATH 3sl3B

3sl3B

PDB Chain 3sl3B

Image of CATH 3sl3C

3sl3C

PDB Chain 3sl3C

Image of CATH 3sl3D

3sl3D

PDB Chain 3sl3D

Image of CATH 3sl3A00

3sl3A00

CATH Domain 3sl3A00

Image of CATH 3sl3B00

3sl3B00

CATH Domain 3sl3B00

Image of CATH 3sl3C00

3sl3C00

CATH Domain 3sl3C00

Image of CATH 3sl3D00

3sl3D00

CATH Domain 3sl3D00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	29 Nov, 2011	Chopped
B	29 Nov, 2011	Chopped
C	29 Nov, 2011	Chopped
D	29 Nov, 2011	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3sl3A00	25 Apr, 2013	1.10.1300.10	Assigned
3sl3B00	25 Apr, 2013	1.10.1300.10	Assigned
3sl3C00	25 Apr, 2013	1.10.1300.10	Assigned
3sl3D00	25 Apr, 2013	1.10.1300.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
Q08499	PDE4D_HUMAN	Homo sapiens	cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Q08499	PDE4D_HUMAN	Homo sapiens	cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Q08499	PDE4D_HUMAN	Homo sapiens	cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Q08499	PDE4D_HUMAN	Homo sapiens	cAMP-specific 3',5'-cyclic phosphodiesterase 4D