Structure-Guided Lead Optimization of Triazolopyrimidine-Ring Substituents Identifies Potent Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors with Clinical Candidate Potential.
Coteron, J.M., Marco, M., Esquivias, J., Deng, X., White, K.L., White, J., Koltun, M., El Mazouni, F., Kokkonda, S., Katneni, K., Bhamidipati, R., Shackleford, D.M., Angulo-Barturen, I., Ferrer, S.B., Jimenez-Diaz, M.B., Gamo, F.J., Goldsmith, E.J., Charman, W.N., Bathurst, I., Floyd, D., Matthews, D., Burrows, J.N., Rathod, P.K., Charman, S.A., Phillips, M.A.
J.Med.Chem.
