PDB 3sff

PDB Information

PDB3SFF
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Human HDAC isoform selectivity achieved via exploitation of the acetate release channel with structurally unique small molecule inhibitors.
Whitehead, L., Dobler, M.R., Radetich, B., Zhu, Y., Atadja, P.W., Claiborne, T., Grob, J.E., McRiner, A., Pancost, M.R., Patnaik, A., Shao, W., Shultz, M., Tichkule, R., Tommasi, R.A., Vash, B., Wang, P., Stams, T.
Bioorg.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2011-06-13
Resolution2.000
CATH Insert Date24 Jul, 2011

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 25 Jul, 2011 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
3sffA00 04 Aug, 2011 3.40.800.20 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q9BY41 HDAC8_HUMAN Homo sapiens Histone deacetylase 8
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