PDB 3s85

PDB Links
Overview

PDB Information

PDB	3S85
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Human immunodeficiency virus 1
Primary Citation	2-Pyridyl P1'-substituted symmetry-based human immunodeficiency virus protease inhibitors (A-792611 and A-790742) with potential for convenient dosing and reduced side effects. Degoey, D.A., Grampovnik, D.J., Flentge, C.A., Flosi, W.J., Chen, H.J., Yeung, C.M., Randolph, J.T., Klein, L.L., Dekhtyar, T., Colletti, L., Marsh, K.C., Stoll, V., Mamo, M., Morfitt, D.C., Nguyen, B., Schmidt, J.M., Swanson, S.J., Mo, H., Kati, W.M., Molla, A., Kempf, D.J. J.Med.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2011-05-27
Resolution	2.800
CATH Insert Date	27 May, 2012

PDB Images (25)

3s85

PDB 3s85

3s85A

PDB Chain 3s85A

3s85B

PDB Chain 3s85B

3s85C

PDB Chain 3s85C

3s85D

PDB Chain 3s85D

3s85E

PDB Chain 3s85E

3s85F

PDB Chain 3s85F

3s85G

PDB Chain 3s85G

3s85H

PDB Chain 3s85H

3s85I

PDB Chain 3s85I

3s85J

PDB Chain 3s85J

3s85K

PDB Chain 3s85K

3s85L

PDB Chain 3s85L

3s85A00

CATH Domain 3s85A00

3s85B00

CATH Domain 3s85B00

3s85C00

CATH Domain 3s85C00

3s85D00

CATH Domain 3s85D00

3s85E00

CATH Domain 3s85E00

3s85F00

CATH Domain 3s85F00

3s85G00

CATH Domain 3s85G00

3s85H00

CATH Domain 3s85H00

3s85I00

CATH Domain 3s85I00

3s85J00

CATH Domain 3s85J00

3s85K00

CATH Domain 3s85K00

3s85L00

CATH Domain 3s85L00

PDB Prints

PDB Chains (12)

Chain ID	Date inserted into CATH	CATH Status
A	28 May, 2012	Chopped
B	28 May, 2012	Chopped
C	28 May, 2012	Chopped
D	28 May, 2012	Chopped
E	28 May, 2012	Chopped
F	28 May, 2012	Chopped
G	28 May, 2012	Chopped
H	28 May, 2012	Chopped
I	28 May, 2012	Chopped
J	28 May, 2012	Chopped
K	28 May, 2012	Chopped
L	28 May, 2012	Chopped

CATH Domains (12)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3s85A00	08 Jun, 2012	2.40.70.10	Assigned
3s85B00	08 Jun, 2012	2.40.70.10	Assigned
3s85C00	08 Jun, 2012	2.40.70.10	Assigned
3s85D00	08 Jun, 2012	2.40.70.10	Assigned
3s85E00	08 Jun, 2012	2.40.70.10	Assigned
3s85F00	08 Jun, 2012	2.40.70.10	Assigned
3s85G00	08 Jun, 2012	2.40.70.10	Assigned
3s85H00	08 Jun, 2012	2.40.70.10	Assigned
3s85I00	08 Jun, 2012	2.40.70.10	Assigned
3s85J00	08 Jun, 2012	2.40.70.10	Assigned
3s85K00	08 Jun, 2012	2.40.70.10	Assigned
3s85L00	08 Jun, 2012	2.40.70.10	Assigned

UniProtKB Entries (12)

Accession	Gene ID	Taxon	Description
P12497	POL_HV1N5	Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)	Gag-Pol polyprotein
P12497	POL_HV1N5	Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)	Gag-Pol polyprotein
P12497	POL_HV1N5	Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)	Gag-Pol polyprotein
P12497	POL_HV1N5	Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)	Gag-Pol polyprotein
P12497	POL_HV1N5	Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)	Gag-Pol polyprotein
P12497	POL_HV1N5	Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)	Gag-Pol polyprotein
P12497	POL_HV1N5	Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)	Gag-Pol polyprotein
P12497	POL_HV1N5	Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)	Gag-Pol polyprotein
P12497	POL_HV1N5	Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)	Gag-Pol polyprotein
P12497	POL_HV1N5	Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)	Gag-Pol polyprotein
P12497	POL_HV1N5	Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)	Gag-Pol polyprotein
P12497	POL_HV1N5	Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)	Gag-Pol polyprotein