PDB 3s4q

PDB Information

PDB3S4Q
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHomo sapiens
Primary Citation
Discovery of pyrrolo[2,1-f][1,2,4]triazine C6-ketones as potent, orally active p38α MAP kinase inhibitors.
Dyckman, A.J., Li, T., Pitt, S., Zhang, R., Shen, D.R., McIntyre, K.W., Gillooly, K.M., Shuster, D.J., Doweyko, A.M., Sack, J.S., Kish, K., Kiefer, S.E., Newitt, J.A., Zhang, H., Marathe, P.H., McKinnon, M., Barrish, J.C., Dodd, J.H., Schieven, G.L., Leftheris, K.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2011-05-20
Resolution2.270
CATH Insert Date05 Feb, 2012

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 06 Feb, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3s4qA01 24 Jan, 2013 3.30.200.20 Assigned
3s4qA02 24 Jan, 2013 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q16539 MK14_HUMAN Homo sapiens Mitogen-activated protein kinase 14