PDB Information

PDB3S3V
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Crystallographic analysis reveals a novel second binding site for trimethoprim in active site double mutants of human dihydrofolate reductase.
Cody, V., Pace, J., Piraino, J., Queener, S.F.
J.Struct.Biol.
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2011-05-18
Resolution1.530
CATH Insert Date02 Oct, 2011

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 29 Nov, 2011 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
3s3vA00 01 Dec, 2011 3.40.430.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P00374 DYR_HUMAN Homo sapiens Dihydrofolate reductase