PDB 3rtm
PDB Information
PDB | 3RTM |
Method | X-RAY DIFFRACTION |
Host Organism | Escherichia coli |
Gene Source | Homo sapiens |
Primary Citation | From Fragment Screening to In Vivo Efficacy: Optimization of a Series of 2-Aminoquinolines as Potent Inhibitors of Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1).
J.Med.Chem.
|
Header | Hydrolase/Hydrolase Inhibitor |
Released | 2011-05-03 |
Resolution | 2.760 |
CATH Insert Date | 04 Sep, 2011 |
PDB Images (4)
PDB Prints
PDB Chains (1)
Chain ID | Date inserted into CATH | CATH Status |
---|---|---|
A | 05 Sep, 2011 | Chopped |
CATH Domains (2)
Domain ID | Date inserted into CATH | Superfamily | CATH Status |
---|---|---|---|
3rtmA01 | 07 Sep, 2011 | 2.40.70.10 | Assigned |
3rtmA02 | 07 Sep, 2011 | 2.40.70.10 | Assigned |
UniProtKB Entries (1)
Accession | Gene ID | Taxon | Description |
---|---|---|---|
P56817 | BACE1_HUMAN | Homo sapiens | Beta-secretase 1 |