PDB Information

PDB3R7R
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Structure-based design of thienobenzoxepin inhibitors of PI3-kinase.
Staben, S.T., Siu, M., Goldsmith, R., Olivero, A.G., Do, S., Burdick, D.J., Heffron, T.P., Dotson, J., Sutherlin, D.P., Zhu, B.Y., Tsui, V., Le, H., Lee, L., Lesnick, J., Lewis, C., Murray, J.M., Nonomiya, J., Pang, J., Prior, W.W., Salphati, L., Rouge, L., Sampath, D., Sideris, S., Wiesmann, C., Wu, P.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2011-03-22
Resolution2.900
CATH Insert Date07 Aug, 2011

PDB Images (7)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 08 Aug, 2011 Chopped

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
3r7rA01 04 Sep, 2013 3.10.20.90 Assigned
3r7rA02 04 Sep, 2013 2.60.40.150 Assigned
3r7rA03 04 Sep, 2013 1.25.40.70 Assigned
3r7rA04 04 Sep, 2013 3.30.1010.10 Assigned
3r7rA05 04 Sep, 2013 1.10.1070.11 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P48736 PK3CG_HUMAN Homo sapiens Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
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