PDB 3r2b

PDB Information

PDB3R2B
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structure-based lead identification of ATP-competitive MK2 inhibitors.
Barf, T., Kaptein, A., Wilde, S., Heijden, R., Someren, R., Demont, D., Schultz-Fademrecht, C., Versteegh, J., Zeeland, M., Seegers, N., Kazemier, B., Kar, B., Hoek, M., Roos, J., Klop, H., Smeets, R., Hofstra, C., Hornberg, J., Oubrie, A.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2011-03-14
Resolution2.900
CATH Insert Date29 May, 2011

PDB Images (37)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 30 May, 2011 Chopped
B 30 May, 2011 Chopped
C 30 May, 2011 Chopped
D 30 May, 2011 Chopped
E 30 May, 2011 Chopped
F 30 May, 2011 Chopped
G 30 May, 2011 Chopped
H 30 May, 2011 Chopped
I 30 May, 2011 Chopped
J 30 May, 2011 Chopped
K 30 May, 2011 Chopped
L 30 May, 2011 Chopped

CATH Domains (24)

Domain ID Date inserted into CATH Superfamily CATH Status
3r2bA01 02 Jun, 2011 3.30.200.20 Assigned
3r2bA02 02 Jun, 2011 1.10.510.10 Assigned
3r2bB01 02 Jun, 2011 3.30.200.20 Assigned
3r2bB02 02 Jun, 2011 1.10.510.10 Assigned
3r2bC01 02 Jun, 2011 3.30.200.20 Assigned
3r2bC02 02 Jun, 2011 1.10.510.10 Assigned
3r2bD01 02 Jun, 2011 3.30.200.20 Assigned
3r2bD02 02 Jun, 2011 1.10.510.10 Assigned
3r2bE01 02 Jun, 2011 3.30.200.20 Assigned
3r2bE02 02 Jun, 2011 1.10.510.10 Assigned
3r2bF01 02 Jun, 2011 3.30.200.20 Assigned
3r2bF02 02 Jun, 2011 1.10.510.10 Assigned
3r2bG01 02 Jun, 2011 3.30.200.20 Assigned
3r2bG02 02 Jun, 2011 1.10.510.10 Assigned
3r2bH01 02 Jun, 2011 3.30.200.20 Assigned
3r2bH02 02 Jun, 2011 1.10.510.10 Assigned
3r2bI01 02 Jun, 2011 3.30.200.20 Assigned
3r2bI02 02 Jun, 2011 1.10.510.10 Assigned
3r2bJ01 02 Jun, 2011 3.30.200.20 Assigned
3r2bJ02 02 Jun, 2011 1.10.510.10 Assigned
3r2bK01 02 Jun, 2011 3.30.200.20 Assigned
3r2bK02 02 Jun, 2011 1.10.510.10 Assigned
3r2bL01 02 Jun, 2011 3.30.200.20 Assigned
3r2bL02 02 Jun, 2011 1.10.510.10 Assigned

UniProtKB Entries (12)

Accession Gene ID Taxon Description
P49137 MAPK2_HUMAN Homo sapiens MAP kinase-activated protein kinase 2
P49137 MAPK2_HUMAN Homo sapiens MAP kinase-activated protein kinase 2
P49137 MAPK2_HUMAN Homo sapiens MAP kinase-activated protein kinase 2
P49137 MAPK2_HUMAN Homo sapiens MAP kinase-activated protein kinase 2
P49137 MAPK2_HUMAN Homo sapiens MAP kinase-activated protein kinase 2
P49137 MAPK2_HUMAN Homo sapiens MAP kinase-activated protein kinase 2
P49137 MAPK2_HUMAN Homo sapiens MAP kinase-activated protein kinase 2
P49137 MAPK2_HUMAN Homo sapiens MAP kinase-activated protein kinase 2
P49137 MAPK2_HUMAN Homo sapiens MAP kinase-activated protein kinase 2
P49137 MAPK2_HUMAN Homo sapiens MAP kinase-activated protein kinase 2
P49137 MAPK2_HUMAN Homo sapiens MAP kinase-activated protein kinase 2
P49137 MAPK2_HUMAN Homo sapiens MAP kinase-activated protein kinase 2