PDB 3qkm

PDB Information

PDB3QKM
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of spirocyclic sulfonamides as potent Akt inhibitors with exquisite selectivity against PKA.
Xu, R., Banka, A., Blake, J.F., Mitchell, I.S., Wallace, E.M., Bencsik, J.R., Kallan, N.C., Spencer, K.L., Gloor, S.L., Martinson, M., Risom, T., Gross, S.D., Morales, T.H., Wu, W.I., Vigers, G.P., Brandhuber, B.J., Skelton, N.J.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2011-02-01
Resolution2.200
CATH Insert Date10 Apr, 2011

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 11 Apr, 2011 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3qkmA01 30 Aug, 2013 3.30.200.20 Assigned
3qkmA02 30 Aug, 2013 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P31749 AKT1_HUMAN Homo sapiens RAC-alpha serine/threonine-protein kinase