PDB 3pp1
PDB Information
| PDB | 3PP1 |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation | Discovery of TAK-733, a potent and selective MEK allosteric site inhibitor for the treatment of cancer.
Bioorg.Med.Chem.Lett.
|
| Header | Transferase/Transferase Inhibitor |
| Released | 2010-11-23 |
| Resolution | 2.700 |
| CATH Insert Date | 27 Feb, 2011 |
PDB Prints
PDB Chains (1)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 28 Feb, 2011 | Chopped |
CATH Domains (2)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 3pp1A01 | 25 Sep, 2013 | 3.30.200.20 | Assigned |
| 3pp1A02 | 25 Sep, 2013 | 1.10.510.10 | Assigned |
UniProtKB Entries (1)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| Q02750 | MP2K1_HUMAN | Homo sapiens | Dual specificity mitogen-activated protein kinase kinase 1 |
