Highly selective c-Jun N-terminal kinase (JNK) 2 and 3 inhibitors with in vitro CNS-like pharmacokinetic properties prevent neurodegeneration.
Probst, G.D., Bowers, S., Sealy, J.M., Truong, A.P., Hom, R.K., Galemmo, R.A., Konradi, A.W., Sham, H.L., Quincy, D.A., Pan, H., Yao, N., Lin, M., Toth, G., Artis, D.R., Zmolek, W., Wong, K., Qin, A., Lorentzen, C., Nakamura, D.F., Quinn, K.P., Sauer, J.M., Powell, K., Ruslim, L., Wright, S., Chereau, D., Ren, Z., Anderson, J.P., Bard, F., Yednock, T.A., Griswold-Prenner, I.
Bioorg.Med.Chem.Lett.
