PDB 3ooz

PDB Information

PDB3OOZ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design and Synthesis of Aminohydantoins as Potent and Selective Human beta-Secretase (BACE1) Inhibitors with Enhanced Brain Permeability
Malamas, M.S., Robichaud, A., Erdei, J., Quagliato, D., Solvibile, W., Zhou, P., Morris, K., Turner, J., Wagner, E., Fan, K., Olland, A., Jacobsen, S., Reinhart, P., Riddell, D., Pangalos, M.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2010-08-31
Resolution1.800
CATH Insert Date04 Sep, 2011

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Sep, 2011 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3oozA01 06 Sep, 2011 2.40.70.10 Assigned
3oozA02 06 Sep, 2011 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
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