PDB Information

PDB3OMK
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHomo sapiens
Primary Citation
Optimization of a novel class of benzimidazole-based farnesoid X receptor (FXR) agonists to improve physicochemical and ADME properties
Richter, H.G.F., Benson, G.M., Bleicher, K.H., Blum, D., Chaput, E., Clemann, N., Feng, S., Gardes, C., Grether, U., Hartman, P., Kuhn, B., Martin, R.E., Plancher, J.M., Rudolph, M.G., Schuler, F., Taylor, S.
Bioorg.Med.Chem.Lett.
HeaderHormone Receptor
Released2010-08-27
Resolution1.900
CATH Insert Date23 Jan, 2011

PDB Images (7)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 24 Jan, 2011 Chopped
B 24 Jan, 2011 Rejected
C 24 Jan, 2011 Chopped
D 24 Jan, 2011 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3omkA00 17 Feb, 2011 1.10.565.10 Assigned
3omkC00 17 Feb, 2011 1.10.565.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q96RI1 NR1H4_HUMAN Homo sapiens Bile acid receptor
Q96RI1 NR1H4_HUMAN Homo sapiens Bile acid receptor
Q15788 NCOA1_HUMAN Homo sapiens Nuclear receptor coactivator 1
Q15788 NCOA1_HUMAN Homo sapiens Nuclear receptor coactivator 1
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