PDB Information

PDB3OAW
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
4-methylpteridinones as orally active and selective PI3K/mTOR dual inhibitors.
Liu, K.K., Bagrodia, S., Bailey, S., Cheng, H., Chen, H., Gao, L., Greasley, S., Hoffman, J.E., Hu, Q., Johnson, T.O., Knighton, D., Liu, Z., Marx, M.A., Nambu, M.D., Ninkovic, S., Pascual, B., Rafidi, K., Rodgers, C.M., Smith, G.L., Sun, S., Wang, H., Yang, A., Yuan, J., Zou, A.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2010-08-05
Resolution2.750
CATH Insert Date26 Sep, 2010

PDB Images (7)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 27 Sep, 2010 Chopped

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
3oawA01 16 Feb, 2011 3.10.20.90 Assigned
3oawA02 16 Feb, 2011 2.60.40.150 Assigned
3oawA03 16 Feb, 2011 1.25.40.70 Assigned
3oawA04 16 Feb, 2011 3.30.1010.10 Assigned
3oawA05 16 Feb, 2011 1.10.1070.11 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P48736 PK3CG_HUMAN Homo sapiens Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
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