PDB Information

PDB3O64
MethodX-RAY DIFFRACTION
Host OrganismTrichoplusia ni
Gene SourceHomo sapiens
Primary Citation
2-(2-Aminothiazol-4-yl)pyrrolidine-based tartrate diamides as potent, selective and orally bioavailable TACE inhibitors.
Dai, C., Li, D., Popovici-Muller, J., Zhao, L., Girijavallabhan, V.M., Rosner, K.E., Lavey, B.J., Rizvi, R., Shankar, B.B., Wong, M.K., Guo, Z., Orth, P., Strickland, C.O., Sun, J., Niu, X., Chen, S., Kozlowski, J.A., Lundell, D.J., Piwinski, J.J., Shih, N.Y., Siddiqui, M.A.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2010-07-28
Resolution1.880
CATH Insert Date24 Apr, 2011

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 25 Apr, 2011 Chopped
B 25 Apr, 2011 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3o64A00 03 May, 2011 3.40.390.10 Assigned
3o64B00 04 May, 2011 3.40.390.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P78536 ADA17_HUMAN Homo sapiens Disintegrin and metalloproteinase domain-containing protein 17
P78536 ADA17_HUMAN Homo sapiens Disintegrin and metalloproteinase domain-containing protein 17