PDB 3o51

PDB Information

PDB3O51
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of a potent, selective, and orally bioavailable pyridinyl-pyrimidine phthalazine aurora kinase inhibitor.
Cee, V.J., Schenkel, L.B., Hodous, B.L., Deak, H.L., Nguyen, H.N., Olivieri, P.R., Romero, K., Bak, A., Be, X., Bellon, S., Bush, T.L., Cheng, A.C., Chung, G., Coats, S., Eden, P.M., Hanestad, K., Gallant, P.L., Gu, Y., Huang, X., Kendall, R.L., Lin, M.H., Morrison, M.J., Patel, V.F., Radinsky, R., Rose, P.E., Ross, S., Sun, J.R., Tang, J., Zhao, H., Payton, M., Geuns-Meyer, S.D.
J.Med.Chem.
HeaderTransferase
Released2010-07-27
Resolution3.200
CATH Insert Date22 Aug, 2010

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 23 Aug, 2010 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3o51A01 17 Feb, 2011 3.30.200.20 Assigned
3o51A02 17 Feb, 2011 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O14965 AURKA_HUMAN Homo sapiens Aurora kinase A
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