PDB 3nzu

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Overview

PDB Information

PDB	3NZU
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Structure-based optimization of pyrazolo-pyrimidine and -pyridine inhibitors of PI3-kinase. Staben, S.T., Heffron, T.P., Sutherlin, D.P., Bhat, S.R., Castanedo, G.M., Chuckowree, I.S., Dotson, J., Folkes, A.J., Friedman, L.S., Lee, L., Lesnick, J., Lewis, C., Murray, J.M., Nonomiya, J., Olivero, A.G., Plise, E., Pang, J., Prior, W.W., Salphati, L., Rouge, L., Sampath, D., Tsui, V., Wan, N.C., Wang, S., Wiesmann, C., Wu, P., Zhu, B.Y. Bioorg.Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2010-07-16
Resolution	2.600
CATH Insert Date	23 Jan, 2011

PDB Images (7)

Image of CATH 3nzu

3nzu

PDB 3nzu

Image of CATH 3nzuA

3nzuA

PDB Chain 3nzuA

Image of CATH 3nzuA01

3nzuA01

CATH Domain 3nzuA01

Image of CATH 3nzuA02

3nzuA02

CATH Domain 3nzuA02

Image of CATH 3nzuA03

3nzuA03

CATH Domain 3nzuA03

Image of CATH 3nzuA04

3nzuA04

CATH Domain 3nzuA04

Image of CATH 3nzuA05

3nzuA05

CATH Domain 3nzuA05

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	24 Jan, 2011	Chopped

CATH Domains (5)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3nzuA01	17 Feb, 2011	3.10.20.90	Assigned
3nzuA02	17 Feb, 2011	2.60.40.150	Assigned
3nzuA03	17 Feb, 2011	1.25.40.70	Assigned
3nzuA04	17 Feb, 2011	3.30.1010.10	Assigned
3nzuA05	17 Feb, 2011	1.10.1070.11	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P48736	PK3CG_HUMAN	Homo sapiens	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform