A Novel Pyrazolo[1,5-a]pyrimidine Is a Potent Inhibitor of Cyclin-Dependent Protein Kinases 1, 2, and 9, Which Demonstrates Antitumor Effects in Human Tumor Xenografts Following Oral Administration.
Heathcote, D.A., Patel, H., Kroll, S.H., Hazel, P., Periyasamy, M., Alikian, M., Kanneganti, S.K., Jogalekar, A.S., Scheiper, B., Barbazanges, M., Blum, A., Brackow, J., Siwicka, A., Pace, R.D., Fuchter, M.J., Snyder, J.P., Liotta, D.C., Freemont, P.S., Aboagye, E.O., Coombes, R.C., Barrett, A.G., Ali, S.
J.Med.Chem.
