PDB Information

PDB3NKX
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling
Molzan, M., Schumacher, B., Ottmann, C., Baljuls, A., Polzien, L., Weyand, M., Thiel, P., Rose, R., Rose, M., Kuhenne, P., Kaiser, M., Rapp, U.R., Kuhlmann, J., Ottmann, C.
Mol.Cell.Biol.
HeaderProtein Binding, Signaling Protein
Released2010-06-21
Resolution2.400
CATH Insert Date19 Sep, 2010

PDB Images (7)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 20 Sep, 2010 Chopped
B 20 Sep, 2010 Chopped
P 20 Sep, 2010 Rejected
Q 20 Sep, 2010 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3nkxA00 16 Feb, 2011 1.20.190.20 Assigned
3nkxB00 16 Feb, 2011 1.20.190.20 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P63104 1433Z_HUMAN Homo sapiens 14-3-3 protein zeta/delta
P63104 1433Z_HUMAN Homo sapiens 14-3-3 protein zeta/delta
P04049 RAF1_HUMAN Homo sapiens RAF proto-oncogene serine/threonine-protein kinase
P04049 RAF1_HUMAN Homo sapiens RAF proto-oncogene serine/threonine-protein kinase
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